Antifungal metabolites of biocontrol stain LB-1 and their inhibition mechanism against Botrytis cinerea.

ABSTRACT:

Introduction

Chaetomium subaffine LB-1 is a novel biocontrol strain that produces non-volatile metabolites that inhibit the growth of Botrytis cinerea. However, the specific metabolites and antimicrobial mechanism of the strain LB-1 remains unclear.

Methods

In this study, the antifungal substances produced by strain LB-1, as well as the underlying mechanism of its inhibitory effect against B. cinerea, were explored using metabolomic and transcriptomic analysis.

Results

The results found that 45 metabolites might be the key antifungal substances, such as ouabain, ferulic acid, chlorogenic acid, spermidine, stachydrine, and stearic acid. The transcriptomic analysis indicated that the inhibition effect of LB-1 on B. cinerea resulted in the upr

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11409189 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature