A roadmap for SHANK3-related Epilepsy Research: recommendations from the 2023 strategic planning workshop.

ABSTRACT: On September 27, 2023, the CureSHANK nonprofit foundation sponsored a conference in Boston, Massachusetts, to identify gaps in knowledge surrounding SHANK3-related epilepsy with the goal of determining future research priorities and recommendations. In addition to patient families and members of the CureSHANK community, participants in the conference included a broad cross-section of preclinical and clinical researchers and clinicians with expertise in SHANK3-related epilepsy as well as representatives from the pharmaceutical industry. Here we summarize the outcomes from comprehensive premeeting deliberations and the final conference recommendations, including (1) gaps in knowledge related to clinical science, (2) gaps in knowledge related to preclinical science, and (3) research prioritie

SUBMITTER: Savage MC 

PROVIDER: S-EPMC11409305 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature