Systematic literature review of the indirect costs and humanistic burden of β-thalassemia.

ABSTRACT:

Background

β-Thalassemia is an inherited blood disorder requiring lifetime management of anemia and its complications.

Objective

This study aimed to determine the indirect costs and humanistic burden of β-thalassemia.

Design

A systematic literature review was conducted.

Data sources and methods

Searches were conducted in Embase, MEDLINE, MEDLINE In-Process, and EconLit (November 1, 2010, to November 25, 2020). Studies reporting indirect costs and health-related quality of life (HRQoL) for patients with β-thalassemia were eligible.

Results

Seventy-five publications were included. Mean annual days lost due to transfusion-related absenteeism ranged from 15.6 to 35 days. Patients spent a mean of 592 min (standard deviation (SD): 349) daily on disease managem

SUBMITTER: Aydinok Y 

PROVIDER: S-EPMC11409307 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature