Comparative effects of drug interventions for the acute management of migraine episodes in adults: systematic review and network meta-analysis.

ABSTRACT:

Objective

To compare all licensed drug interventions as oral monotherapy for the acute treatment of migraine episodes in adults.

Design

Systematic review and network meta-analysis.

Data sources

Cochrane Central Register of Controlled Trials, Medline, Embase, ClinicalTrials.gov, EU Clinical Trials Register, WHO International Clinical Trials Registry Platform, as well as websites of regulatory agencies and pharmaceutical companies without language restrictions until 24 June 2023.

Methods

Screening, data extraction, coding, and risk of bias assessment were performed independently and in duplicate. Random effects network meta-analyses were conducted for the primary analyses. The primary outcomes were the proportion of participants who were pain-free at two hours po

SUBMITTER: Karlsson WK 

PROVIDER: S-EPMC11409395 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature