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Association between base excess and mortality in critically ill patients with ischemic stroke: a retrospective cohort study.


ABSTRACT:

Background

Base excess (BE) is associated with mortality from many diseases. However, the relationship between BE and mortality in patients with ischemic stroke remains uncertain. Our aim is to investigate the relationship between BE values upon admission to the ICU and mortality rates in critically ill stroke patients.

Methods

The current study enrolled 1,572 patients with ischemic stroke (863 males and 709 females). The associations of BE with intensive care unit (ICU), hospital, 28-day, and 1-year mortalities were assessed using multivariable logistic regression or Cox proportional hazards model. The potential impact of the Sequential Organ Failure Assessment (SOFA) score (< 5 or ≥ 5) on the prognostic value of BE was further evaluated with interaction and subgroup analys

SUBMITTER: Liu J 

PROVIDER: S-EPMC11409610 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature