From raw milk cheese to the gut: investigating the colonization strategies of <i>Bifidobacterium mongoliense</i>.

ABSTRACT: The microbial ecology of raw milk cheeses is determined by bacteria originating from milk and milk-producing animals. Recently, it has been shown that members of the Bifidobacterium mongoliense species may become transmitted along the Parmigiano Reggiano cheese production chain and ultimately may colonize the consumer intestine. However, there is a lack of knowledge regarding the molecular mechanisms that mediate the interaction between B. mongoliense and the human gut. Based on 128 raw milk cheeses collected from different Italian regions, we isolated and characterized 10 B. mongoliense strains. Comparative genomics allowed us to unveil the presence of enzymes required for the degradation of sialylated host-glycans in B. mongoliense, corroborating the appreciab

SUBMITTER: Longhi G 

PROVIDER: S-EPMC11409640 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature