Genetic history and biological adaptive landscape of the Tujia people inferred from shared haplotypes and alleles.

ABSTRACT:

Background

High-quality genomic datasets from under-representative populations are essential for population genetic analysis and medical relevance. Although the Tujia are the most populous ethnic minority in southwestern China, previous genetic studies have been fragmented and only partially reveal their genetic diversity landscape. The understanding of their fine-scale genetic structure and potentially differentiated biological adaptive features remains nascent.

Objectives

This study aims to explore the demographic history and genetic architecture related to the natural selection of the Tujia people, focusing on a meta-Tujia population from the central regions of the Yangtze River Basin.

Results

Population genetic analyses conducted on the meta-Tujia people indicate

SUBMITTER: Chen J 

PROVIDER: S-EPMC11409738 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature