Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo.

ABSTRACT: The Democratic Republic of Congo (DRC) suffers from one of the highest malaria burdens worldwide, but information on its Anopheles vector populations is relatively limited. Preventative malaria control in DRC is reliant on pyrethroid-treated nets, raising concerns over the potential impacts of insecticide resistance. We sampled Anopheles gambiae from three geographically distinct populations (Kimpese, Kapolowe and Mikalayi) in southern DRC, collecting from three sub-sites per population and characterising mosquito collections from each for resistance to pyrethroids using WHO tube bioassays. Resistance to each of three different pyrethroids was generally high in An. gambiae with < 92% mortality in all tests, but varied between collections, with mosquitoes from Kimpese being the most resista

SUBMITTER: Dennis TPW 

PROVIDER: S-EPMC11410927 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature