Quantitation of mitral regurgitation using positron emission tomography.

ABSTRACT:

Background

Cardiac positron emission tomography (PET) offers non-invasive assessment of perfusion and left ventricular (LV) function from a single dynamic scan. However, no prior assessment of mitral regurgitation severity by PET has been presented. Application of indicator dilution techniques and gated image analyses to PET data enables calculation of forward stroke volume and total LV stroke volume. We aimed to evaluate a combination of these methods for measurement of regurgitant volume (RegVol) and fraction (RegF) using dynamic ¹⁵O-water and ¹¹C-acetate PET in comparison to cardiovascular magnetic resonance (CMR).

Results

Twenty-one patients with severe primary mitral valve regurgitation underwent same-day dynamic PET examinations (¹⁵O-wa

SUBMITTER: Sigfridsson J 

PROVIDER: S-EPMC11411051 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature