Changes in electrophysiological aperiodic activity during cognitive control in Parkinson's disease.

ABSTRACT: Cognitive symptoms in Parkinson's disease are common and can significantly affect patients' quality of life. Therefore, there is an urgent clinical need to identify a signature derived from behavioural and/or neuroimaging indicators that could predict which patients are at increased risk for early and rapid cognitive decline. Recently, converging evidence identified that aperiodic activity of the EEG reflects meaningful physiological information associated with age, development, cognitive and perceptual states or pathologies. In this study, we aimed to investigate aperiodic activity in Parkinson's disease during cognitive control and characterize its possible association with behaviour. Here, we recorded high-density EEG in 30 healthy controls and 30 Parkinson's disease patients during a S

SUBMITTER: Monchy N 

PROVIDER: S-EPMC11411214 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature