Efficient DNP at high fields and fast MAS with antenna-sensitized dinitroxides.

ABSTRACT: Dynamic Nuclear Polarization (DNP) can significantly enhance the sensitivity of solid-state NMR. In DNP, microwave irradiation induces polarization transfer from unpaired electron spins to ¹H nuclear spins via hyperfine couplings and spin-diffusion. The structure of the polarizing agents that host the electron spins is key for DNP efficiency. Currently, only a handful of structures perform well at very high magnetic fields (≥18.8 T), and enhancements are significantly lower than those obtained at lower fields. Here, we introduce a new series of water-soluble nitroxide biradicals with a scaffold augmented by dihydroxypropyl antenna chains that perform significantly better than previous dinitroxides at 18.8 T. The new radical M-TinyPol(OH)₄ yields enhancement fac

SUBMITTER: Niccoli L 

PROVIDER: S-EPMC11411413 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature