Tailoring Risk Prediction Models to Local Populations.

ABSTRACT:

Importance

Risk estimation is an integral part of cardiovascular care. Local recalibration of guideline-recommended models could address the limitations of existing tools.

Objective

To provide a machine learning (ML) approach to augment the performance of the American Heart Association's Predicting Risk of Cardiovascular Disease Events (AHA-PREVENT) equations when applied to a local population while preserving clinical interpretability.

Design, setting, and participants

This cohort study used a New England-based electronic health record cohort of patients without prior atherosclerotic cardiovascular disease (ASCVD) who had the data necessary to calculate the AHA-PREVENT 10-year risk of developing ASCVD in the event period (2007-2016). Patients with prior ASCVD events,

SUBMITTER: Zinzuwadia AN 

PROVIDER: S-EPMC11411452 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature