Quantification of Lanthanides on a PMMA Microfluidic Device with Three Optical Pathlengths Using PCR of UV-Visible, NIR, and Raman Spectroscopy.

ABSTRACT: Microfluidic devices (MFDs) offer customizable, low-cost, and low-waste platforms for performing chemical analyses. Optical spectroscopy techniques provide nondestructive monitoring of small sample volumes within microfluidic channels. Optical spectroscopy can probe speciation, oxidation state, and concentration of analytes as well as detect counterions and provide information about matrix composition. Here, ultraviolet-visible (UV-vis) absorbance, near-infrared (NIR) absorbance, and Raman spectroscopy are utilized on a custom poly(methyl methacrylate) (PMMA) MFD for the detection of three lanthanide nitrates in solution. Absorbance spectroscopies are conducted across three pathlengths using three portions of a contiguous channel within the MFD. Univariate and chemometric multivariate mode

SUBMITTER: Lackey HE 

PROVIDER: S-EPMC11411548 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature