Enhanced Electrochemical Detection of Nonelectroactive Compounds Based on Surface Supramolecular Interactions on Chevron-like Graphene Nanoribbons Modified through Click Chemistry.

ABSTRACT: In this study, we have developed a nanostructured electrochemical sensor based on modified graphene nanoribbons tailored for the analysis of nonelectroactive compounds via a surface competitive assay. Stigmasterol, a nonelectroactive phytosterol, was selected as a representative case. Chevron-like graphene nanoribbons, chemically synthesized, were immobilized onto glassy carbon electrodes and covalently functionalized to allow the on-surface formation of a supramolecular complex. To this end, the nanoribbons were first modified through a diazotization process by electrochemical reduction of a 4-azidoaniline diazonium salt, leaving the electrode surface with azide groups exposed to solution. Next, the incorporation of a ferrocene group, as a redox probe, was carried out by a click chemistry

SUBMITTER: Martinez-Moro R 

PROVIDER: S-EPMC11411676 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature