Socioeconomic Inequalities in the External Exposome in European Cohorts: The EXPANSE Project.

ABSTRACT: Socioeconomic inequalities in the exposome have been found to be complex and highly context-specific, but studies have not been conducted in large population-wide cohorts from multiple countries. This study aims to examine the external exposome, encompassing individual and environmental factors influencing health over the life course, and to perform dimension reduction to derive interpretable characterization of the external exposome for multicountry epidemiological studies. Analyzing data from over 25 million individuals across seven European countries including 12 administrative and traditional cohorts, we utilized domain-specific principal component analysis (PCA) to define the external exposome, focusing on air pollution, the built environment, and air temperature. We conducted linear

SUBMITTER: Saucy A 

PROVIDER: S-EPMC11411702 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature