Multiresponsive 4D Printable Hydrogels with Anti-Inflammatory Properties.

ABSTRACT: Multiresponsive hydrogels are valuable as biomaterials due to their ability to respond to multiple biologically relevant stimuli, i.e., temperature, pH, or reactive oxygen species (ROS), which can be present simultaneously in the body. In this work, we synthesize triple-responsive hydrogels through UV light photopolymerization of selected monomer compositions that encompass thermoresponsive N-isopropylacrylamide (NIPAM), pH-responsive methacrylic acid (MAA), and a tailor-made ROS-responsive diacrylate thioether monomer (EG₃SA). As a result, smart P[NIPAM_x-co-MAA_y-co-(EG₃SA)_z] hydrogels capable of being manufactured by digital light processing (DLP) 4D printing are obtained. The thermo-, pH-, an

SUBMITTER: Regato-Herbella M 

PROVIDER: S-EPMC11411719 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature