Long-term outcomes in rapamycin on renal allograft function: a 30-year follow-up from a single-center experience.

ABSTRACT:

Objectives

To evaluate long-term renal graft prognosis and the role of rapamycin from a single-center in China over a 30-year follow-up.

Methods

This study enrolled a total of 654 patients who underwent kidney transplantation between 1989 and 2020. The basic characteristics of the included patients were collected. Graft survival was described and compared using Kaplan-Meier curves (K-M curves). Both continuous and categorical variables were included in a multivariate Cox proportional-hazards model. Patients were divided into rapamycin-based quadruple immunosuppression regimen group (rapa group, n = 41) and conventional tacrolimus-based triple immunosuppression regimen group (control group, n = 218). The indication biopsy results of the two groups were further reviewed to com

SUBMITTER: Ji Y 

PROVIDER: S-EPMC11411783 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature