<i>N</i>-linked protein glycosylation in <i>Nanobdellati</i> (formerly DPANN) archaea and their hosts.

ABSTRACT: Members of the kingdom Nanobdellati, previously known as DPANN archaea, are characterized by ultrasmall cell sizes and reduced genomes. They primarily thrive through ectosymbiotic interactions with specific hosts in diverse environments. Recent successful cultivations have emphasized the importance of adhesion to host cells for understanding the ecophysiology of Nanobdellati. Cell adhesion is often mediated by cell surface carbohydrates, and in archaea, this may be facilitated by the glycosylated S-layer protein that typically coats their cell surface. In this study, we conducted glycoproteomic analyses on two co-cultures of Nanobdellati with their host archaea, as well as on pure cultures of both host and non-host archaea. Nanobdellati exhibited various glycopr

SUBMITTER: Nakagawa S 

PROVIDER: S-EPMC11411935 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature