Evaluation of serum irisin level and severity of erectile dysfunction in diabetic males: a cross sectional prospective study.

ABSTRACT:

Background

Irisin is an exercise-induced myokine that alleviates endothelial dysfunction and reduces insulin resistance in type 2 diabetes mellitus (T2DM). The current study aimed to assess the serum level of irisin in T2DM men with erectile dysfunction (ED) compared to T2DM patients with normal erectile function and healthy controls, as well as investigate the association between serum irisin level and the severity of ED in T2DM patients.

Patients and methods

A cross-sectional study was conducted on 90 males, divided into three groups: 32 T2DM patients with ED, 24 T2DM patients without ED, and 34 healthy controls. Socio-demographic characteristics and scores of the validated Arabic version of the international Index of Erectile Function-5 (ArIIEF-5), Generalized Anxiety Dis

SUBMITTER: Ragab A 

PROVIDER: S-EPMC11412007 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature