Whole genome sequence analysis of population structure and insecticide resistance markers in Anopheles melas from the Bijagos Archipelago, Guinea-Bissau.

ABSTRACT:

Background

Anopheles melas is an understudied malaria vector with a potential role in malaria transmission on the Bijagós Archipelago of Guinea-Bissau. This study presents the first whole-genome sequencing and population genetic analysis for this species from the Bijagós. To our knowledge, this also represents the largest population genetic analysis using WGS data from non-pooled An. melas mosquitoes.

Methods

WGS was conducted for 30 individual An. melas collected during the peak malaria transmission season in 2019 from six different islands on the Bijagós Archipelago. Bioinformatics tools were used to investigate the population structure and prevalence of insecticide resistance markers in this mosquito population.

Results

Insecticide resistance mutations associated w

SUBMITTER: Moss S 

PROVIDER: S-EPMC11412053 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature