Associations of behavioral problems with white matter circuits connecting to the frontal lobes in school-aged children born at term and preterm.

ABSTRACT:

Introduction

This study investigated whether internalizing and externalizing behavioral problems in children were associated with fractional anisotropy of white matter tracts connecting other brain regions to the frontal lobes. We contrasted patterns of association between children born at term (FT) and very preterm (PT: gestational age at birth =< 32 weeks).

Methods

Parents completed the Child Behavior Checklist/6-18 questionnaire to quantify behavioral problems when their children were age 8 years (N = 36 FT and 37 PT). Diffusion magnetic resonance scans were collected at the same age and analyzed using probabilistic tractography. Multiple linear regressions investigated the strength of association between age-adjusted T-scores of internalizing and externalizing problems a

SUBMITTER: Hosoki M 

PROVIDER: S-EPMC11412113 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature