Fetal and neonatal echocardiographic analysis of biomechanical alterations for the systemic right ventricle heart.

ABSTRACT:

Background

The perinatal transition's impact on systemic right ventricle (SRV) cardiac hemodynamics is not fully understood. Standard clinical image analysis tools fall short of capturing comprehensive diastolic and systolic measures of these hemodynamics.

Objectives

Compare standard and novel hemodynamic echocardiogram (echo) parameters to quantify perinatal changes in SRV and healthy controls.

Methods

We performed a retrospective study of 10 SRV patients with echocardiograms at 33-weeks gestation and at day of birth and 12 age-matched controls. We used in-house developed analysis algorithms to quantify ventricular biomechanics from four-chamber B-mode and color Doppler scans. Cardiac morphology, hemodynamics, tissue motion, deformation, and flow parameters were meas

SUBMITTER: Meyers BA 

PROVIDER: S-EPMC11412552 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature