Effect of propofol versus midazolam on short-term outcomes in patients with sepsis-associated acute kidney injury.

ABSTRACT:

Background

Propofol and midazolam are commonly used sedative drugs in mechanically ventilated patients in the Intensive Care Unit (ICU). However, there is still a lack of relevant studies exploring the influence of midazolam and propofol on the prognosis of patients with Sepsis-associated Acute Kidney Injury (S-AKI).

Patients and methods

A statistical analysis was conducted on 3,745 patients with S-AKI in the Medical Information Mart for Intensive Care IV database. The patients' baseline characteristics were grouped based on the use of either propofol or midazolam as sedatives. Cox proportional hazards models, logistic regression models, and subgroup analyses were used to compare the effects of propofol and midazolam on the short-term prognosis of S-AKI patients, including 3

SUBMITTER: Li Y 

PROVIDER: S-EPMC11412802 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature