Examining the association between prenatal and perinatal adversity and the psychotic experiences in childhood.

ABSTRACT:

Background

Prenatal and perinatal complications are established risk factors for psychotic disorder, but far less is known about these measures and psychotic experiences (PEs). We investigated the longitudinal effect of prenatal risk factors (maternal behavior, medication complications) and perinatal risk factors (birth weight, medical complications) on frequency of PEs. We also examined the cumulative risk of prenatal/perinatal risk factors, and differences between transient PE, persistent PE, and controls.

Methods

The Adolescent Brain Cognitive Development study is a large child cohort (age 9-10 at baseline; n = 11 872 with PE data). PEs were measured longitudinally using the Prodromal Questionnaire-Brief, Child version, and included only if reported as distressing.

SUBMITTER: Staines L 

PROVIDER: S-EPMC11413340 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature