Long-Term Use of Muscle Relaxant Medications for Chronic Pain: A Systematic Review.

ABSTRACT:

Importance

Stricter opioid prescribing guidelines have increased prescriptions of skeletal muscle relaxants (SMRs) for chronic pain, but the efficacy of long-term use of SMRs for chronic pain is unknown.

Objective

To systematically review the effectiveness or efficacy of long-term use of SMRs for chronic pain.

Evidence review

Two reviewers systematically searched Ovid MEDLINE, Embase (Ovid), Web of Science, CINAHL, and Cochrane through December 4, 2023. They included articles published in English, Spanish, or Italian. Only randomized clinical trials (RCTs) and cohort studies with comparator groups evaluating at least 1-month duration of SMRs for chronic pain were included. The reviewers dually reviewed data abstraction, risk-of-bias, and quality. They characterized st

SUBMITTER: Oldfield BJ 

PROVIDER: S-EPMC11413720 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature