Dysfunction in interpersonal neural synchronization as a mechanism for social impairment in autism spectrum disorder.

ABSTRACT: Social deficits in autism spectrum disorder (ASD) have been linked to atypical activation of the mentalizing network. This work, however, has been limited by a focus on the brain activity of a single person during computerized social tasks rather than exploring brain activity during in vivo interactions. The current study assessed neural synchronization during a conversation as a mechanism for social impairment in adults with ASD (n = 24) and matched controls (n = 26). Functional near-infrared spectroscopy (fNIRS) data were collected from the prefrontal cortex (PFC) and tempoparietal junction (TPJ). Participants self-reported on their social communication and videos of the interaction were coded for utterances and conversational turns. As expected, controls showed more neural synchrony tha

SUBMITTER: Quinones-Camacho LE 

PROVIDER: S-EPMC11413982 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature