Increased predictive value of optical spectral transmission in early rheumatoid arthritis through use of patient-adjusted cut-off scores.

ABSTRACT:

Objectives

The aims of this study were to suggest patient-adjusted optical spectral transmission (OST) cut-off values for the first time and to develop clinical models that predict the probability of an early rheumatoid arthritis (RA) diagnosis based on OST findings and the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria as a reference standard.

Methods

OST examinations were performed in newly diagnosed RA patients and healthy controls by the HandScan device. Moreover, RA patients underwent a full clinical [tender/swollen joint counts (TJC/SJC), disease activity score-28 (DAS28)] and laboratory evaluation. OST confounding factors were examined via logistic multivariate regression analyses and patient-adjusted OST-c

SUBMITTER: Triantafyllias K 

PROVIDER: S-EPMC11414023 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature