Contact X-ray Brachytherapy as a sole treatment in selected patients with early rectal cancer - Multi-centre study.

ABSTRACT:

Background and purpose

Radical surgery is the standard of care for early rectal cancer. However, alternative organ-preserving approaches are attractive, especially in frail or elderly patients as these avoid surgical complications. We have assessed the efficacy of sole Contact X-ray Brachytherapy (CXB) treatment in stage-1 rectal cancer patients who were unsuitable for or declined surgery.

Materials and methods

This retrospective multi-centre study (2009-2021) evaluated 76 patients with T1/2-N0-M0 rectal adenocarcinomas who were treated with CXB alone. Outcomes were assessed for the entire cohort and sub-groups based on the T-stage and the criteria for receiving CXB alone; Group A: patients who were fit enough for surgery but declined, Group B: patients who were high-risk fo

SUBMITTER: Wah Than N 

PROVIDER: S-EPMC11414538 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature