Reduced heart rate variability is associated with altered clinical laboratory profile in people living with HIV.

ABSTRACT:

Background

We compared heart rate variability (HRV) indices between people living with HIV (PLWH) and HIV-negative individuals to ascertain the independent association between HIV infection and reduced HRV, and further investigated whether distinct clinical laboratory profiles exist between PLWH with and without reduced HRV.

Methods

This cross-sectional analysis included 304 PLWH and 147 HIV-negative individuals with comparable age and sex. Thirty-two routine clinical laboratory indices (including hematology and biochemistry) closest to the survey were extracted from the Electronic Medical Record System. HRV indices were divided into two categories: low (lowest quartile, Q1) and moderate-to-high (combined, Q2‒Q4).

Results

The time domain indices, ln(SDNN), ln(RMSSD),

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11414568 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature