Finite element model reveals the involvement of cartilage endplate in quasi-static biomechanics of intervertebral disc degeneration.

ABSTRACT:

Background and objective

The intrinsic link between the compositional and structural attributes and the biomechanical functionality is evident in intervertebral discs. However, it remains unclear from a biomechanical perspective whether cartilage endplate (CEP) degeneration exacerbates intervertebral disc degeneration.

Methods

This study developed and quantitatively validated four biphasic swelling-based finite element models. We then applied four quasi-static tests and simulated daily loading scenarios to examine the effects of CEP degradation.

Results

Under free-swelling conditions, short-term responses were prevalent, with CEP performance changes not significantly impacting response proportionality. The creep test results showed the more than 50 % of the strain was

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11414571 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature