Remote levodopa challenge test in Parkinson's disease: Feasibility, reliability, validity and economic value.

ABSTRACT:

Background and purpose

The aim was to demonstrate the feasibility, reliability and validity of an in-home remote levodopa challenge test (LCT), as delivered through an online platform, for patients with Parkinson's disease (PwPD).

Methods

Patients with Parkinson's disease eligible for deep brain stimulation surgery screening were enrolled. Participants sequentially received an in-home remote LCT and an in-hospital standard LCT (separated by 2.71 weeks). A modified Movement Disorder Society Unified Parkinson's Disease Rating Scale Part III omitting rigidity and postural stability items was used in the remote LCT. The reliability of the remote LCT was evaluated using the intraclass correlation coefficient and the concurrent validity was evaluated using the Pearson's correlatio

SUBMITTER: Zeng Z 

PROVIDER: S-EPMC11414795 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature