Heterogeneity of Treatment Effects of Laser Epilation on Pilonidal Disease Recurrence: A Randomized Clinical Trial.

ABSTRACT:

Objective

To investigate the heterogeneity of treatment effects (HTE) of laser epilation in preventing pilonidal disease recurrence through analysis of prespecified clinical factors.

Background

Pilonidal disease is a common, painful disease affecting 1% of the population aged 15 to 30 years with postoperative recurrence rates as high as 30% to 40%.

Methods

Single-institution randomized controlled trial from September 2017 to September 2022 with 1-year follow-up, including patients aged 11 to 21 years with pilonidal disease undergoing gluteal cleft laser epilation and standard care (improved hygiene and mechanical or chemical depilation) or standard care alone.

Results

In total, 302 patients were enrolled with 151 randomized to each intervention. 1-year follow-u

SUBMITTER: Bergus KC 

PROVIDER: S-EPMC11415133 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature