Hepatocellular Carcinoma Surveillance Patterns and Outcomes in Patients With Cirrhosis.

ABSTRACT:

Background & aims

Hepatocellular carcinoma (HCC) surveillance is associated with improved early detection and reduced mortality, although practice patterns and effectiveness vary in clinical practice. We aimed to characterize HCC surveillance patterns in a large, diverse cohort of patients with HCC.

Methods

We conducted a retrospective cohort study of patients diagnosed with HCC between January 2008 and December 2022 at 2 large US health systems. We recorded imaging receipt in the year before HCC diagnosis: ultrasound plus α-fetoprotein (AFP), ultrasound alone, multiphasic contrast-enhanced computed tomography (CT)/magnetic resonance imaging (MRI), and no liver imaging. We used multivariable logistic and Cox regression analysis to compare early tumor detection, curative trea

SUBMITTER: Daher D 

PROVIDER: S-EPMC11415236 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature