Early-Life Risk Factors for Carotid Intima-Media Thickness and Carotid Stiffness in Adolescence.

ABSTRACT:

Importance

Atherogenesis starts during childhood, making childhood and adolescence an important window of opportunity to prevent atherosclerotic cardiovascular disease later in life.

Objective

To identify early-life risk factors for preclinical atherosclerosis in adolescence.

Design, setting, and participants

This cohort study is part of the ongoing Wheezing Illness Study in Leidsche Rijn (WHISTLER) prospective birth cohort study, which includes 3005 healthy newborns born between December 2001 and December 2012 in the Leidsche Rijn area of Utrecht, the Netherlands. Eligible participants included those from the WHISTLER cohort who visited the clinic between March 2019 and October 2020 for adolescent follow-up. This study's analyses were performed in January 2024.

Ex

SUBMITTER: van der Linden IA 

PROVIDER: S-EPMC11415786 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature