Tramadol use in U.S. Adults With Commercial Health Insurance, 2005-2021.

ABSTRACT:

Introduction

Tramadol has been associated with chronic opioid use and emergency room (ER) visits. However, little is known about trends in prescription tramadol use in the U.S.

Methods

Optum's de-identified Clinformatics® Data Mart Database was used to assess trends in monthly incident and prevalent tramadol use from 2005 to 2021, stratified by sex and age (18-64 vs. ≥65 years). State-specific trends following scheduling of tramadol as Class IV controlled substance in August 2014 were analyzed with random effects regression models. Demographics, comorbidities, initiation setting, dose, and co-dispensing with other opioids and central nervous system (CNS) agents were assessed in people initiating tramadol, stratified by age and initiation year (2005-2010, 2011-2015, 2016-2021

SUBMITTER: Basham CA 

PROVIDER: S-EPMC11416325 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature