Stereotactic body radiotherapy is an alternative to radiofrequency ablation for single HCC ≤5.0 cm.

ABSTRACT:

Background & aims

Radiation therapy has been refined with increasing evidence of the benefits of stereotactic body radiation therapy (SBRT) in treating hepatocellular carcinoma (HCC). In this study, we aimed to evaluate whether SBRT could serve as an alternative to radiofrequency ablation (RFA) for small HCC with a single lesion ≤5.0 cm.

Methods

Patients with a single HCC lesion ≤5.0 cm who received RFA or SBRT were included. Cumulative local/distant recurrence rate, progression-free survival, overall survival, adverse events and subsequent treatments after recurrence were analyzed.

Results

A total of 288 patients receiving RFA (n = 166) or SBRT (n = 122) were enrolled. The baseline characteristics between the two groups were comparable. The cumulative local recurrenc

SUBMITTER: Yang Z 

PROVIDER: S-EPMC11416668 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature