Maximum spherical mean value filtering for whole-brain QSM.

ABSTRACT:

Purpose

To develop a tissue field-filtering algorithm, called maximum spherical mean value (mSMV), for reducing shadow artifacts in QSM of the brain without requiring brain-tissue erosion.

Theory and methods

Residual background field is a major source of shadow artifacts in QSM. The mSMV algorithm filters large field-magnitude values near the border, where the maximum value of the harmonic background field is located. The effectiveness of mSMV for artifact removal was evaluated by comparing existing QSM algorithms in numerical brain simulation as well as using in vivo human data acquired from 11 healthy volunteers and 93 patients.

Results

Numerical simulation showed that mSMV reduces shadow artifacts and improves QSM accuracy. Better shadow reduction, as demonstrated

SUBMITTER: Roberts AG 

PROVIDER: S-EPMC11416845 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature