Quantitative ²³Na magnetic resonance imaging in the abdomen at 3 T.

ABSTRACT:

Objectives

To assess the feasibility of sodium-23 MRI for performing quantitative and non-invasive measurements of total sodium concentration (TSC) and relaxation in a variety of abdominal organs.

Materials and methods

Proton and sodium imaging of the abdomen was performed in 19 healthy volunteers using a 3D cones sequence and a sodium-tuned 4-rung transmit/receive body coil on a clinical 3 T system. The effects of B₁ non-uniformity on TSC measurements were corrected using the double-angle method. The long-component of ²³Na T₂* relaxation time was measured using a series of variable echo-times.

Results

The mean and standard deviation of TSC and long-component ²³Na T₂* values were calculated across the healthy volu

SUBMITTER: Birchall JR 

PROVIDER: S-EPMC11417083 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature