Physiology-inspired bifocal fronto-parietal tACS for working memory enhancement.

ABSTRACT: Aging populations face significant cognitive challenges, particularly in working memory (WM). Transcranial alternating current stimulation (tACS) offer promising avenues for cognitive enhancement, especially when inspired by brain physiology. This study (NCT04986787) explores the effect of multifocal tACS on WM performance in healthy older adults, focusing on fronto-parietal network modulation. Individualized physiology-inspired tACS applied to the fronto-parietal network was investigated in two blinded cross-over experiments. The first experiment involved monofocal/bifocal theta-tACS to the fronto-parietal network, while in the second experiment cross-frequency theta-gamma interactions between these regions were explored. Participants have done online WM tasks under the stimulation condit

SUBMITTER: Pupikova M 

PROVIDER: S-EPMC11417162 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature