Blood pressure, brain lesions and cognitive decline in patients with atrial fibrillation.

ABSTRACT:

Background

The influence of atrial fibrillation (AF) and blood pressure (BP) on brain lesions and cognitive function is unclear. We aimed to investigate the association of BP with different types of brain lesions and cognitive decline in patients with AF.

Methods

Overall, 1,213 AF patients underwent standardized brain magnetic resonance imaging at baseline and after 2 years, as well as yearly neurocognitive testing. BP was measured at baseline and categorized according to guidelines. New lesions were defined as new or enlarged brain lesions after 2 years. We defined cognitive decline using three different neurocognitive tests. Logistic and Cox regression analyses were performed to examine the associations of BP with new brain lesions and cognitive decline.

Results

The

SUBMITTER: Carmine D 

PROVIDER: S-EPMC11417621 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature