Preliminary results on temporal evolution and clinical implications of atherosclerotic plaque in branch atheromatous disease after statin treatment.

ABSTRACT:

Background

Branch atheromatous disease (BAD) is a primary cause of early neurological deterioration (END) in penetrating artery occlusion, leading to poor functional outcomes. While it has been proposed to classify BAD under large artery atherosclerosis, uncertainty exists regarding the optimal treatment strategy, including cholesterol-lowering targets.

Objectives

We aimed to assess the clinical implications and temporal changes of atherosclerotic plaques before and after high-intensity statin treatment.

Design

This is a high-resolution vessel-wall imaging sub-analysis of the trial of Statin and Dual Antiplatelet Therapy in Preventing Early Neurological Deterioration in Branch Atheromatous Disease (SATBRAD).

Methods

In this prospective, single-group cohort stud

SUBMITTER: Huang YC 

PROVIDER: S-EPMC11418250 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature