Advances in DNA methylation of imprinted genes and folic acid regulation of growth and development.

ABSTRACT: DNA methylation is closely related to folate levels and acts as a mechanism linking developmental disorders to chronic diseases. Folic acid supplementation can impact DNA methylation levels of imprinted genes crucial for neonatal development. Imprinted genes are vital for regulating embryonic and postnatal fetal growth. This review summarizes imprinted genes, DNA methylation, folic acid's influence on growth and development and their correlation. It aims to provide a comprehensive overview of research advancements on imprinted genes, DNA methylation and folic acid regulation concerning growth and development.

SUBMITTER: Guo X 

PROVIDER: S-EPMC11418287 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature