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Case fatality and functional outcome after spontaneous subarachnoid haemorrhage: A systematic review and meta-analysis of time trends and regional variations in population-based studies.


ABSTRACT:

Introduction

A previous systematic review of population-based studies from 1973 to 2002 found a decrease in case fatality for spontaneous subarachnoid haemorrhage, but could not find a sufficient number of studies to assess changes in functional outcome. Since then, treatment has advanced distinctly. We assessed whether case fatality has decreased further and whether functional outcome has improved.

Patients and methods

We searched PubMed and Web of Science for new population-based studies using the same criteria as in our previous systematic review. We assessed changes in case fatality and functional outcome over time using linear regression.

Results

We included 24 new studies with 827 patients and analysed 9542 patients described in 62 study periods between 1973 and

SUBMITTER: Ziebart A 

PROVIDER: S-EPMC11418425 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature