Clinical course of patients with conservatively managed cerebral cavernous malformations.

ABSTRACT:

Introduction

There is uncertainty whether patients with a cerebral cavernous malformation (CCM) should undergo conservative or surgical treatment, resulting in practice variation among hospitals. Our objective was to report clinical outcomes of patients with primarily conservatively managed CCMs.

Patients and methods

This single-center cohort study included consecutive adult CCM patients, diagnosed in 2000-2023, who underwent conservative management as primary treatment strategy. Data were extracted from medical records, and we systematically conducted telephone and questionnaire follow-up. Functional status was assessed on the modified Rankin Scale (mRS).

Results

Of 345 patients, we included 265 patients with a CCM (median age 46 years; 45% male). At baseline, 131 (4

SUBMITTER: Sandmann ACA 

PROVIDER: S-EPMC11418428 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature