Medication adherence to inhalation therapy and the risk of COPD exacerbations: a systematic review with meta-analysis.

ABSTRACT:

Background

Assessing medication adherence is crucial in chronic obstructive pulmonary disease (COPD) management to prevent exacerbations. However, it is unclear whether this association between adherence and exacerbations is influenced by the adherence assessment methods or thresholds used. Electronic healthcare databases are valuable to study exacerbations and adherence in real life. We aimed to systematically review the literature to identify adherence assessment methods and thresholds used in healthcare databases when investigating the association between medication adherence and COPD exacerbations and to meta-analyse the associated effect sizes.

Method

MEDLINE, Web of Science and Embase were searched for peer-reviewed articles, written in English, published up to 10 Octo

SUBMITTER: Vauterin D 

PROVIDER: S-EPMC11418573 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature