<i>Track-A-Worm 2.0</i>: A Software Suite for Quantifying Properties of <i>C. elegans</i> Locomotion, Bending, Sleep, and Action Potentials.

ABSTRACT: Comparative analyses of locomotor behavior and cellular electrical properties between wild-type and mutant C. elegans are crucial for exploring the gene basis of behaviors and the underlying cellular mechanisms. Although many tools have been developed by research labs and companies, their application is often hindered by implementation difficulties or lack of features specifically suited for C. elegans. Track-A-Worm 2.0 addresses these challenges with three key components: WormTracker, SleepTracker, and Action Potential (AP) Analyzer. WormTracker accurately quantifies a comprehensive set of locomotor and body bending metrics, reliably distinguish between the ventral and dorsal sides, continuously tracks the animal using a motorized stage, an

SUBMITTER: Vedantham K 

PROVIDER: S-EPMC11418985 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature