A Systematic Review of Air Pollution Exposure and Brain Structure and Function during Development.

ABSTRACT:

Objectives

Air pollutants are known neurotoxicants. In this updated systematic review, we evaluate new evidence since our 2019 systematic review on the effect of outdoor air pollution exposure on childhood and adolescent brain structure and function as measured by magnetic resonance imaging (MRI).

Methods

Using PubMed and Web of Science, we conducted an updated literature search and systematic review of articles published through March 2024, using key terms for air pollution and functional and/or structural MRI. Two raters independently screened all articles using Covidence and implemented the risk of bias instrument for systematic reviews informing the World Health Organization Global Air Quality Guidelines.

Results

We identified 222 relevant papers, and 14 new studi

SUBMITTER: Morrel J 

PROVIDER: S-EPMC11419233 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature