Living donors kidney transplantation and oxidative stress: Nitric oxide as a predictive marker of graft function.

ABSTRACT:

Background

Glomerular filtration rate is the best indicator of renal function and a predictor of graft and patient survival after kidney transplantation.

Methods

In a single-centre prospective analysis, we assessed the predictive performances of 4 oxidative stress biomarkers in estimating graft function at 6 months and 1 year after kidney transplantation from living donors. Blood samples were achieved on days (D-1, D1, D2, D3, D6 and D8), months (M1, M3 and M6) and after one year (1Y). For donors, a blood sample was collected on D-1. Malondialdehyde (MDA), nitric oxide (NO), glutathione s-transferase (GST), myeloperoxydase (MPO), and creatinine (Cr) were measured by spectrophotometric essays. The estimated glomerular filtration rate by the modification of diet in renal disea

SUBMITTER: Izemrane D 

PROVIDER: S-EPMC11419388 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature