Causal association between blood metabolites and vertigo: A Mendelian randomization study.

ABSTRACT: Metabolic disorders have been identified as an important factor causing nervous system diseases. However, due to the interference of confounding factors, the causal relationship between them has not been clearly elucidated, so it is necessary to study the causal relationship between them. To explore the causal relationship between blood metabolites and vertigo by Mendelian randomization. To assess causality, the inverse variance weighting method was employed as the primary analytical approach, complemented by additional sensitivity analyses. Metabolic pathway enrichment analysis and genetic correlation analysis were employed to further assess the metabolites. All statistical analyses were conducted using the R software. The study employed metabolite Genome Wide Association Study and vertig

SUBMITTER: Zhang B 

PROVIDER: S-EPMC11419507 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature