Efficacy and safety of serrapeptase on ankle sprain cases: A single center prospective comparative study.

ABSTRACT:

Background

Non-steroid anti-inflammatory drugs (NSAIDs) rank among the frequently prescribed medications for addressing pain and inflammation. Although they are powerful pain relievers, their side effects are indisputable. Serrapeptase, a serine protease, exhibits anti-inflammatory and anti-oedemic activity without the side effects of NSAIDs. We aim to assess the efficacy and safety of serrapeptase in the treatment of pain and edema in ankle sprains.

Methods

In a single-centre prospective comparative study, 76 patients aged 18-53 with Grade II ankle sprains were assigned to either a serrapeptase intervention group (n = 38) receiving 5 mg serrapeptase (two tablets, three times per day) for ten days, or a control group (n = 38) receiving 500 mg paracetamol (three times per day

SUBMITTER: Stamati A 

PROVIDER: S-EPMC11419880 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature